Dismiss Modal

Diagnosis

Blood Culture

Choose a preferred language


Does this test have other names?

Blood culture and sensitivity test, blood C&S


What is this test?

This blood test finds out if you have a systemic infection. This is an infection that affects your whole body, not just one part. A sample of blood is studied in a lab to check for bacteria or for a type of fungus called yeast.


Why do you need this test?

You may need this test if you have symptoms of a systemic infection. These include:

  • Chills.

  • Fever or low temperature.

  • Severe tiredness (fatigue).

  • Confusion.

  • Nausea.

  • Fast breathing or heart rate.

  • Passing urine less often.

  • Cough.

A blood culture and sensitivity test can be done to confirm an infection, such as pneumonia, and figure out the best way to treat it.


What other tests might you have along with this test?

If your health care provider believes you have pneumonia, a test called a Gram stain may be done on a sample of sputum, which is mucus that you cough up. This helps find out what is causing the infection.

You may also have susceptibility testing. This test finds out which antibiotic can treat your infection. You may also have a complete blood count (CBC) either before or with the blood culture. The CBC test shows if you have a higher level of white blood cells, which can also be a sign of infection. Your urine may also be tested to check for infection.

The blood culture test may need to be repeated if it comes back negative but you still have symptoms. It may also be repeated after you take antibiotics to make sure the infection is gone.


What do your test results mean?

Test results may vary depending on your age, gender, health history, and other things. Your test results may be different depending on the lab used. They may not mean you have a problem. Ask your health care provider what your test results mean for you.

A positive result means bacteria or yeast are present in your blood. A negative result means that no signs of any bacteria or yeast were found in your blood.


How is this test done?

The test is often done with at least two blood samples, drawn through a needle from different veins. Taking multiple samples is more likely to produce accurate results. The blood samples are placed in bottles with a substance that promotes growth of bacteria or yeast. This is called a culture.

Early results may be available in 24 hours. But it can take 48 to 72 hours to find out the specific bacteria or yeast causing your infection.


Does this test pose any risks?

Having a blood test with a needle carries some risks. These include bleeding, infection, bruising, and feeling lightheaded. When the needle pricks your arm or hand, you may feel a slight sting or pain. Afterward, the site may be sore.


What might affect your test results?

Antibiotic medicine could slow the growth of the infecting bacteria. If possible, the blood sample should be drawn just before you begin taking antibiotics.


How do you get ready for this test?

You don't need to prepare for this test. If you are taking antibiotics, let your health care provider know the time of your last dose. Tell your provider about all medicines, herbs, vitamins, and supplements you are taking. This includes medicines that don't need a prescription and any illegal drugs you may use.

Author: Orenstein, Beth W.

© 2000-2025 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Get Connected to a Care Manager

Get Connected
Related Articles
Read article
Hematology
Acetaminophen Drug Level

The acetaminophen drug level is a blood test used to screen for the presence of the common pain reliever acetaminophen.

Read article
Hematology
Helicobacter Pylori Culture

This test is used to find out if you are infected with Helicobacter pylori bacteria.

Read article
Hematology
Mercury (Blood)

This test measures the amount of mercury in your blood. You can be exposed to mercury from polluted air or water, if you work in an industry that still uses mercury, from eating fish that are high in mercury, and from some complementary and alternative health remedies.

Read article
Hematology
Parathyroid Hormone

This test measures a substance called parathyroid hormone in your blood. This hormone is needed to help regulate the level of calcium in your blood.